Senior Scientist

Allogene Therapeutics
Posted on


Senior researcher / group leader

Your browser cookies must be enabled in order to apply for this job. Please contact if you need further instruction on how to do that. Senior Scientist, Analytical Development Job Description

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T™) therapies for cancer. Led by a world-class management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell therapy candidates with the goal of delivering readily available cell therapy faster, more reliably and at greater scale to more patients.

AlloCAR T™ cell therapies are engineered from cells of healthy donors, which is intended to allow for creation of inventory for on demand use in patients. This approach is designed to eliminate the need to create personalized therapy from a patient’s own cells, simplify manufacturing, and reduce the time patients must wait for CAR T cell treatment. The Allogene portfolio includes rights to 16 pre-clinical CAR T cell therapy targets and UCART19, an AlloCAR T™ therapy candidate currently in Phase 1 sponsored by Servier for the treatment of relapsed/refractory acute lymphoblastic leukemia (ALL). For more information, please visit, and follow @AllogeneTx on Twitter and LinkedIn.



We are seeking a highly motivated Senior Scientist to join our analytical development team. The selected candidate will be responsible for developing cell-based characterization, in-process and release assays to support process development and manufacturing, then transferring selected assays to QC or CRO.


Responsibilities include, but are not limited to:

  • Select, design and implement cell-based analytical methods to test process intermediates, drug substances and drug products during process development
  • Exercise independent judgment in performing experimental methods, techniques, evaluation criteria for obtaining results, and data analysis
  • Evaluate and transfer in appropriate assays and improve their performance
  • Provide technical input to enhance current analytical methods
  • Write protocols and development reports, and contribute to relevant regulatory filings
  • Tech transfer selected assays to in-house and CMO QC groups
  • As needed, support specification setting, qualification and validation of assays
  • Present scientific results in team meetings and at conferences


Position Requirements & Experience:

  • A PhD or equivalent in Immunology, Cell Biology or related field with 5+ years of assay development experience in biotech
  • Experience in executing cellular characterization via cell functional assays, PCR and imaging platforms is required
  • Experience with assay qualification and validation is plus
  • Familiarity with FDA, ICH and GMP guidelines is preferred
  • Highly organized, detail-oriented individual with strong analytical and problem-solving skills
  • Excellent written, verbal and interpersonal skills
  • Ability to multi-task within a highly collaborative, fast-paced environment


As an equal opportunity employer, Allogene Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact the careers email at for assistance.



More Information

Posted on


Senior researcher / group leader


South San Francisco , United States